Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors during the central anxious system, conolidine modulates alternate molecular targets. A Science Innovations examine discovered that conolidine interacts Together with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide av... https://optimusbookmarks.com/story20341213/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers