At 3 times post-MPTP, we located sizeable microglial activation and up-regulation of CB2 cannabinoid receptors in the ventral midbrain. Procedure with Earn or even the CB2 receptor agonist JWH015 (four mg/kg, intraperitoneal) decreased MPTP-induced microglial activation, While genetic ablation of CB2 receptors exacerbated MPTP systemic toxicity. In addition, Long-term Earn https://win55.clinic/tin-tuc